Biosketch

I am a researcher and Genomics scientist working in the field of human microbiome and Genomics at the SKAN Research Institute. My research interests focus on understanding Role of gut microbiome in health and diseases, Gut microbiome community structure and interactions with host, germline & somatic variants in various diseases.

I completed my PHD in experimental medicine (Genomics) from the Instituto Politécnico Nacional Escuela Superior de Medicina (IPN-ESM), Mexico and completed my post-doctoral training at Manipal School of life sciences, MAHE, India. During my PhD and postdoctoral research, I investigated genomic, transcriptomic, and microbiome changes across a range of disease conditions. After completing my postdoctoral training, I served as the lead/head for the sequencing facility and the Personalized Medicine and Oncology division at a private diagnostics company.

In addition to my wet lab research, I have also contributed significantly and is one of the authors of SciDAVis (SciDAVis – Wikipedia) and a fork of the same called Alpha Plot (AlphaPlot download | SourceForge.net).

As part of the SKAN–Quadram Institute Bioscience (QIB) collaboration, Dr. Arun Narayanankutty served as a Visiting Scientist at QIB from April to July 2025. During this period, he worked on the standardization of TraDIS-Xpress in clinical strains of Klebsiella pneumoniae. The primary objective of this work was to optimize the protocol and facilitate technology transfer to SKAN.

Research Focus

Publications

1. Falfán-Valencia R, Narayanankutty A, Reséndiz-Hernández JM, Pérez-Rubio G, Ramírez-Venegas A, Nava-Quiroz KJ, Bautista-Félix NE, Vargas-Alarcón G, Castillejos-López MDJ, Hernández A. An Increased Frequency in HLA Class I Alleles and Haplotypes Suggests Genetic Susceptibility to Influenza A (H1N1) 2009 Pandemic: A Case-Control Study. J Immunol Res. 2018 Feb 25;2018:3174868. doi: 10.1155/2018/3174868. PMID: 29682588; PMCID: PMC5845504.
2. Narayanankutty A, Palma-Lara I, Pavón-Romero G, Pérez-Rubio G, Camarena Á, Teran LM, Falfán-Valencia R. Association of TRPM3 Polymorphism (rs10780946) and Aspirin-Exacerbated Respiratory Disease (AERD). Lung. 2016 Apr;194(2):273-9. doi: 10.1007/s00408-016-9852-9. Epub 2016 Feb 18. PMID: 26891941.
3. Narayanankutty A, Reséndiz-Hernández JM, Falfán-Valencia R, Teran LM. Biochemical pathogenesis of aspirin exacerbated respiratory disease (AERD). Clin Biochem. 2013 May;46(7-8):566-78. doi: 10.1016/j.clinbiochem.2012.12.005. Epub 2012 Dec 13. PMID: 23246457.

Additional Information

Invited Talk :

• Next generation sequencing & Data analysis, Dr. MGR Educational & Research Institute deemed to be university, March 2025.

  Conferences & workshops :

  • Single-Cell & Spatial Symposium, Earlham Institute, Norwich, UK, June 2025

Grants

Press Releases

Professional Profiles

Team Members

• Ganesh Nair (Technician, 2025 to present)

Collaborations

Biosketch

Ritika completed her PhD from Jawaharlal Nehru University (JNU), New Delhi. Her doctoral research focused on studying the aggregation of myocilin protein and its modulation, using biophysical techniques and computational analysis.Her research interest lies in studying protein misfolding and aggregation in neurodegenerative diseases. Currently at SKAN-RT, she is studying how the gut environment can influence the amyloidosis of human alpha-synuclein protein, implicated in Parkinson’s Disease.

Research Focus

• Protein Biophysics
• Protein Aggregation and Amyloidosis
• Neurodegeneration

Publications

1. Sharma R. Advanced immunotherapy across diseases and the role of artificial intelligence: A review. Biomol Biomed. 2026 Jan 28. doi: 10.17305/bb.2026.13199. Epub ahead of print. PMID: 41603677.
2. Admane N, Srivastava A, Jamal S, Sharma R, Kundu B, Grover A. Molecular insights into the critical role of gallate moiety of green tea catechins in modulating prion fibrillation, cellular internalization, and neuronal toxicity. International Journal of Biological Macromolecules. 2022 Nov 9.
3. Sharma R, Kumari A, Kundu B, Grover A. Amyloid fibrillation of the glaucoma associated myocilin protein is inhibited by epicatechin gallate (ECG). RSC advances. 2022;12(45):29469-81.
4. Bhardwaj A, Sharma R, Grover A. Immuno-informatics guided designing of a multi epitope vaccine against Dengue and Zika. Journal of Biomolecular Structure and Dynamics. 2021 Nov 6:1-5.
5. Sharma R, Grover A. Myocilin-associated Glaucoma: A Historical Perspective and Recent Research Progress. Molecular Vision. 2021; 27:480.
6. Rajput VS, Sharma R, Kumari A, Vyas N, Prajapati V, Grover A. Engineering a multi epitope vaccine against SARS-CoV-2 by exploiting its non-structural and structural proteins. Journal of Biomolecular Structure and Dynamics. 2021 May 26:1-8.
7. Kumari A, Sharma R, Somvanshi P and Grover A. Assessing the role of osmolytes on the conformational harmony of islet amyloid polypeptide. International Journal of Biological Macromolecules. 2020; 164, 2569.
8. Kumari A, Sharma R, Shrivastava N, Somvanshi P and Grover A. Bleomycin modulates amyloid aggregation in β-amyloid and hIAPP. RSC Advances. 2020; 10(43), 25929.
9. Kumar P, Sharma R, Jaiswal V, Chauhan RS. Identification, validation, and expression of ABC transporters in Podophyllum hexandrum and their role in podophyllotoxin biosynthesis. Biologia plantarum. 2016 Sep; 60(3):452-8.

Additional Information

Grants

Press Releases

Professional Profiles

Team Members

Collaborations

Biosketch

Dr. Madhav Kumar is a faculty member at SKAN Research Trust with expertise in microbiology, gut microbiome research, bioinformatics, and bacteriophages. He earned his Ph.D. from CSIR–Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), India, where his doctoral work focused on biofilm-forming bacteria and their biotechnological applications, including dye degradation, agarose production, and extracellular polymeric substance isolation.

As part of the SKAN–Quadram Institute Bioscience (QIB) collaboration, Dr. Kumar served as a Visiting Scientist at QIB from February 2024 to March 2025. During this period, he conducted in-depth studies on the gut microbiome of Parkinson’s disease patients and successfully isolated and characterized multiple bacterial strains from clinical samples.

At SKAN Research Trust, his current research focuses on understanding host–microbe interactions and exploring the therapeutic potential of bacteriophages, particularly against sulfur-reducing bacteria associated with Parkinson’s disease and other disorders. With a strong interdisciplinary background in microbiology and computational biology, Dr. Kumar aims to develop targeted, microbiome-based therapeutic strategies and advance translational research in human health.

Research Focus

1. Gut Microbiome and Human Health
   Investigation of gut microbial composition and function, with a focus on their role in neurological and systemic disorders, particularly Parkinson’s disease.
2. Bacteriophages and Phage-Based Therapeutics
   Isolation, characterization, and application of bacteriophages as targeted therapeutic agents against pathogenic and disease-associated bacteria.
3. Sulfur-Reducing Bacteria in Disease
   Study of sulfur-reducing gut bacteria and their contribution to disease pathogenesis, with emphasis on identifying strategies to modulate their activity.
4. Clinical Microbiology and Bacterial Isolation
   Culture-based isolation and characterization of clinically relevant bacterial strains from patient samples, including anaerobic and fastidious organisms.
5. Colon Model Studies for Gut Microbiome Modulation
   Use of in vitro colon and gut simulation models to study microbial interactions, community dynamics, and targeted modulation of the gut microbiome under controlled conditions.

Publications

1. Kumar, M., Agrawal, D., Khoiyangbam, R. S., Chingangbam, S. S., & Chaudhary, D. R. (2026). Seasonal variations in functional gene abundances and potential methane production across different vegetation types in coastal soils of Gujarat, India. Regional Studies in Marine Science, 104757.
2. Kumar, M.*, Sayavedra, L., Baker, D.J., Shouche, Y.S., and Narbad, A. (2025). Genome sequence of Eubacterium callanderi AM6, isolated from a Parkinson’s disease patient. Microbiology Resource Announcements, 14:e00039-25.
3. Kumar, R., Kumar, M., Tanna, B., and Bhargava, B. (2025). Molecular diagnostic techniques utilized in viral diseases. In Viral Diseases (Book Chapter).
4. Kumar, M., and Chaudhary, D.R. (2024). Agarose degrading potential and whole genome sequence analysis of marine bacterium Aliagarivorans sp. strain DM1 isolated from the Arabian Sea. Current Microbiology.
   Kumar, M., Soni, R., Saran, P., and Chaudhary, D.R. (2024). Characterization of extracellular polymeric substances from biofilm-forming marine bacteria from the Arabian Sea, India. Indian Journal of Microbiology.
5. Chaudhary, D.R., Kumar, M., and Kalla, V. (2023). Sediment microbial community structure and functional gene abundance in coastal hypersaline habitats. Archives of Microbiology, 205, 56.
6. Kumar, M., Kumari, A., Vaghani, B.P., and Chaudhary, D.R. (2023). Dye degradation by early colonizing marine bacteria from the Arabian Sea, India. Archives of Microbiology, 205, 160.
7. Kumar, M., Chaudhary, D.R., and Jha, B. (2023). Surface-associated bacterial assemblages on marine anthropogenic litter in the intertidal zone of the Arabian Sea, India. Marine Pollution Bulletin, 193, 115211.
8. Khandare, S., Teotia, N., Kumar, M., Diyora, P., and Chaudhary, D.R. (2023). Biodegradation and decolorization of trypan blue azo dye by marine bacteria Vibrio sp. JM-17. Biocatalysis and Agricultural Biotechnology, 5, 102802.
9. Kumar, M., Kumar, R., Chaudhary, D.R., and Jha, B. (2022). An appraisal of early-stage biofilm-forming bacterial community assemblage and diversity in the Arabian Sea, India. Marine Pollution Bulletin, 180, 113732.

Additional Information

• Invited talk on “From colon to cortex: mapping the microbiome’s role in disease progression”, at Carmel college of Arts, Science & Commerce for women, Department of food technology, Goa. January 2026

• Participated in 6^th International conference on Bacteriophage research and antimicrobial resistance at Banaras Hindu University (BHU), Varanasi (November 12-13, 2025)
• Participated in 6^th International workshop on Bacteriophage research and antimicrobial resistance at Banaras Hindu University (BHU), Varanasi (November 09-11, 2025)
• Attended Festival of Genomics & Biodata conference at London ExCeL (January 29-30, 2025)
• Attended John Innes Centre (JIC)/ The Sainsbury Laboratory (TSL) annual science meeting at Norwich, UK (October 9-11, 2024)
• Participated in workshop “Grant writing using AI” at Norwich, UK (July 29-30, 2024)
• Participated in Indo-US international conference on antimicrobial resistance and human microbiome at THSTI, Faridabad (November 15-16, 2023)
• Oral presentation in Online International Conference on Research Methodology at Lucknow, UP (October 28-30, 2022)
• Served as the resource person for the workshop “Next Generation Sequencing”, held at Amrita School of Biotechnology (January 31, 2020)
• Served as the resource person for the training “next generation sequence – data analysis” held at UniBiosys research labs (October 22, 2019)
• Poster presentation and participation in XXXII Gujarat science congress (February 4-5, 2018)

Grants

Press Releases

Professional Profiles

Team Members

• Mahesh Mulajkar (Technician; 2025 to Present)
• Mrugank Mrugesh Walimbe (Intern 2025 to Present)

• 👤 Aratrika Das (Intern; 2025)
• 👤 Disha V Rao (Intern; 2025)
• 👤 Mahendra Pratap Singh (Intern; 2025)
• 👤 Ritika Sharma (Intern; 2025)
• 👤 Diyanesh Waran (Intern; 2025)
• 👤 Arko Guha (Intern; 2025)
• 👤 Arjun Raj (Intern; 2025)
• 👤 Aratrika (Intern; 2024)
• 👤 Manasvi (Intern; 2023)

Collaborations

• Quadram Institute , Norwich, United Kingdom
• St. John’s Research Institute , Koramangala, Bengaluru
• National Institute of Mental Health & Neuro Sciences (NIMHANS) , Bengaluru

Biosketch

I am a researcher and stem cell scientist working in the field of leukemia and bone marrow transplantation at the SKAN Research Institute. My research interests focus on understanding hematopoietic stem cell (HSC) biology and the role of the bone marrow microenvironment (BMM) in regulating normal hematopoiesis, as well as its dysregulation in pathological conditions such as leukemia and aging.

I earned my Ph.D. in Biotechnology from the National Centre for Cell Science (NCCS), India, affiliated with the University of Pune. I subsequently completed postdoctoral training at INSERM, France, and at The Ohio State University and the University of Utah, USA. During my postdoctoral research, I investigated the molecular mechanisms regulating HSC function, leukemogenesis, and stem cell–microenvironment interactions.

Currently, at the SKAN Research Institute, my research focuses on elucidating the role of the bone marrow microenvironment in normal hematopoiesis and defining the dynamic niche alterations that occur during malignant, non-malignant and neuro-immune disorders, with the goal of identifying novel targets for therapeutic intervention.

Research Focus

1. Altered Bone Marrow Niche in Leukemia and Blood Disorders:
   We investigate structural and functional alterations in the bone marrow niche during leukemia and other hematological disorders to identify niche-driven mechanisms that promote disease progression and to develop strategies for restoring normal hematopoietic support.
2. Role of Extracellular Vesicles in Hematopoiesis and Leukemia:
   Our lab studies the role of extracellular vesicles, including microvesicles and exosomes, in regulating hematopoietic stem and progenitor cell (HSPC) fate and function. We focus on elucidating the molecular cargo transferred via extracellular vesicles and how this intercellular communication contributes to leukemogenesis and disruptions in normal hematopoiesis.
3. Rejuvenation of Aged Hematopoietic Stem Cells (HSCs):
   We explore molecular and cellular interventions to rejuvenate aged hematopoietic stem cells and restore their regenerative capacity, with implications for improving immune function during aging and enhancing responses to therapeutic interventions.
4. Impact of Maternal and Fetal Stressors on Lifelong Hematopoiesis:
   We examine how maternal stress signals influence fetal hematopoietic development and long-term immune programming. Understanding these maternal–fetal interactions is critical for identifying early-life determinants of susceptibility to hematopoietic and immune disorders.
5. Hematopoiesis and the Bone Marrow Niche in Neuro-Immune Disorders:
   We investigate how dysregulation of hematopoiesis and alterations in the bone marrow niche contribute to the onset and progression of neuro-immune disorders. By dissecting niche–immune interactions, we aim to identify novel cellular and molecular targets that modulate immune dysregulation and disease progression.

Publications

1. Papaioannou, D., Urs, A.P., Buisson, R., Petri, A., Liu, M., Woodward, L., Kulkarni, R., Weislämle, X., Ivashkiv, O., Nicolet, D. and Goda, C., 2026. circPCMTD1: A protein-coding circular RNA that regulates DNA damage response in BCR/ABL1-positive leukemias. Blood Journal, pp.blood-2025031129.
2. Kulkarni, R., Bustos, Y., Rudich, A., Karunasiri, M., Urs, A., Balcioglu, O., Li, W., Chidester, S., Rodgers, K., Garfinkle, E. and Patel, A., 2025. Epithelial growth factor like-7 (EGFL7) regulates hematopoiesis stem cell (HSC) activation via AP-1 suppression. Blood, 146, p.209.
3. Rodgers, K., Mifflin, K., Kigerl, K., Hall, J., Kulkarni, R., Garfinkle, E., Asghari, E., Wang, C., Lai, W., Guan, Z. and Karunasiri, M., 2025. Disrupted DNA repair and oxidative stress responses underlie hematopoietic stem cell failure after spinal cord injury. Blood,146, p.3204.
4. Rondina, M., Banerjee, M., Kulkarni, R., Goda, C., Balcioglu, O., Chidester, S., Bustos, Y. and Dorrance, A., 2025. Preserving stemness: Targeting interferon-sensitive genes to mitigate inflammatory hematopoietic stress. Experimental Hematology, 151, p.105235.
5. Kulkarni, R., Goda, C., Rudich, A., Karunasiri, M., Urs, A.P., Bustos, Y., Balcioglu, O., Li, W., Chidester, S., Rodgers, K.A. and Garfinkle, E.A., 2026. Regulation of hematopoietic stem cell (HSC) proliferation by Epithelial Growth Factor Like-7 (EGFL7). bioRxiv, pp.2025-01.
6. Goda, C., Kulkarni, R., Bustos, Y., Li, W., Rudich, A., Balcioglu, O., Chidester, S., Urs, A.P., Karunasiri, M., Al-Marrawi, Y. and Korn, E., 2025. Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia. Leukemia, 39(1), pp.51-63. (co-first author)
7. Rodgers, K.A., Garfinkle, E.A., Kigerl, K.A., Adib, E.A., Mifflin, K.A., Hall, J., Kulkarni, R., Wang, C., Goda, C., Dias, A.C.R. and Guan, Z., 2025. Transcriptional and epigenetic repression of hematopoietic stem cells underlies bone marrow failure after spinal cord injury. bioRxiv, pp.2025-10.
8. Zhao, J., Cui, Y., Zhou, H., Zhou, D., Che, Z., Zhang, N., Yun, Q., Machado-Neto, J.A., Damiani, D., Al-Kzayer, L.A.F.Y. and Kulkarni, R., 2024. FLT3 mutation-related immune checkpoint molecule absent in melanoma 2 (AIM2) contributes to immune infiltration in pediatric and adult acute myeloid leukemia: evidence from bioinformatics analysis. Translational Cancer Research, 13(11), p.6255.
9. Urs, A.P., Goda, C. and Kulkarni, R., 2024. Remodeling of the bone marrow microenvironment during acute myeloid leukemia progression. Annals of Translational Medicine, 12(4), p.63. (co-first author)
10. Goda, C., Kolovich, S., Rudich, A., Karunasiri, M., Kulkarni, R., Rajgolikar, G., Neidemire-Colley, L., Singh, S., Sircar, A., Ranganathan, P. and Garzon, R., 2023. Epidermal growth factor-like 7 is a novel therapeutic target in mantle cell lymphoma. Experimental Hematology, 123, pp.28-33.
11. Barroca, V., Henry, E., Dechamps, N., Renou, L., Chaintreuil, P., Kulkarni, R., Devanand, S., Jacquel, A., Robert, G., Auberger, P. and Pflumio, F., 2022. REDD1 is a gatekeeper of murine hematopoietic stem cell functions during stress responses. Leukemia, 36(8), pp.2140-2143.
12. Kulkarni, R., 2022. Early growth response factor 1 in aging hematopoietic stem cells and leukemia. Frontiers in Cell and Developmental Biology, 10, p.925761.
13. Dorrance, A.M., Moutuou, M.M., Goda, C., Sell, N.E., Kalyan, S., Karunasiri, M., Kulkarni, R., Goulard, M., Kolovich, S., Rudich, A. and Naumann, E., 2022. Modulating endothelial cells with EGFL7 to diminish aGVHD after allogeneic bone marrow transplantation in mice. Blood Advances, 6(7), pp.2403-2408.
14. Bill, M., Goda, C., Pepe, F., Ozer, H.G., McNeil, B., Zhang, X., Karunasiri, M., Kulkarni, R., Kalyan, S., Papaioannou, D. and Ferenchak, G., 2021. Targeting BRD4 in acute myeloid leukemia with partial tandem duplication of the MLL gene. haematologica, 106(9), p.2527.
15. Shinde, P., Kuhikar, R., Kulkarni, R., Khan, N., Limaye, L. and Kale, V., 2021. Curcumin restores the engraftment capacity of aged hematopoietic stem cells and also reduces PD‐1 expression on cytotoxic T cells. Journal of tissue engineering and regenerative medicine, 15(4), pp.388-400. (co-first author)
16. Kulkarni, R. and Kale, V., 2020. Physiological cues involved in the regulation of adhesion mechanisms in hematopoietic stem cell fate decision. Frontiers in Cell and Developmental Biology, 8, p.611.
17. Kulkarni, R., Bajaj, M. and Kale, V., 2018. Role of Autophagy in Aging of Hematopoietic Stem Cells and Their Niche: Relevance in Clinical Transplantations and Regenerative Medicine. In Autophagy in Health and Disease: Potential Therapeutic Approaches (pp. 31-45). Cham: Springer International Publishing.
18. Kulkarni, R., Bajaj, M. and Kale, V., 2018. Induction and detection of autophagy in aged hematopoietic stem cells by exposing them to microvesicles secreted by HSC-supportive mesenchymal stromal cells. In Autophagy in Differentiation and Tissue Maintenance: Methods and Protocols (pp. 21-34). New York, NY: Springer New York.
19. Kulkarni, R., Bajaj, M., Ghode, S., Jalnapurkar, S., Limaye, L. and Kale, V., 2018. Intercellular transfer of microvesicles from young mesenchymal stromal cells rejuvenates aged murine hematopoietic stem cells. Stem Cells, 36(3), pp.420-433.
20. Ghode, S., Bajaj, M., Kulkarni, R., Limaye, L., Shouche, Y. and Kale, V., 2017. Neuropilin-1 is an important niche component and exerts context-dependent effects on hematopoietic stem cells. Stem Cells and Development, 26(1), pp.35-48.
21. Bajaj, M., Kulkarni, R., Ghode, S., Limaye, L. and Kale, V., 2016. Irradiation-induced secretion of BMP4 by marrow cells causes marrow adipogenesis post-myelosuppression. Stem cell research, 17(3), pp.646-653.
22. Bajaj, M., Ghode, S., Kulkarni, R., Limaye, L. and Kale, V., 2015. Simvastatin improves hematopoietic stem cell engraftment by preventing irradiation-induced marrow adipogenesis and radio-protecting the niche cells. Haematologica, 100(8), p.e323.
23. Nagarkar, B., Kulkarni, R., Bhondave, P., Kasote, D., Kulkarni, O., Harsulkar, A. and Jagtap, S., 2013. Comparative hepatoprotective potential of Tinospora cordifolia, Tinospora sinensis and Neem-guduchi. British Journal of Pharmaceutical Research, 3(4), p.906.

Additional Information

Grants

1. Outstanding Author 2024: In 2024, many ATM authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers. [Link]
2. Young Investigator Award (YIA) 2019: Rohan Kulkarni, Ph.D., has been named the recipient of the 2019 STEM CELLS Young Investigator Award (YIA). The YIA is awarded annually to a young scientist whose paper is judged to be of worldwide significance by a global jury. [Link]
3. EMBL Corporate Partnership Programme Travel Grant 2016
4. Department of Biotechnology, Government of India Travel Grant 2016

Press Releases

1. Rohan Kulkarni named winner of STEM CELLS Young Investigator Award [Link]
2. Indian scientists develop mechanism to rejuvenate aged stem cells [Link]
3. Building a Strong Research Path [Link]
4. Interviews with Outstanding Authors (2024) [Link]

Professional Profiles

Team Members

Collaborations

Biosketch

Dr Ankita Dhenge is a dynamic and results-driven Senior Scientist with extensive experience in stem cell biology, cellular and molecular biology, and translational research. She has led multidisciplinary research projects spanning hematopoiesis, megakaryocyte biology, platelet biogenesis, cell line development and Yeast Antibody discovery projects.

She completed her PhD in Biotechnology from the National Centre for Cell Science (NCCS), Pune, where her work focused on the role of Valproic Acid and polyunsaturated fatty acids in megakaryocyte differentiation and platelet biogenesis. She further expanded her expertise during her postdoctoral fellowship at the University of North Carolina, Chapel Hill, investigating Rap1 GTPase signalling and integrin signalling mechanisms in megakaryocytes.

Dr Dhenge has substantial industry experience from Syngene International (Syngene Amgen Research Centre), where she established stable cell line development workflows, performed cell line characterisation and banking, and led bioassay troubleshooting initiatives. Currently, she is contributing to stem cell research initiatives focused on aging-related and neurological disorders in the Indian population.

She combines strong scientific rigour with project management expertise (Executive Program in Project Management – IIM Lucknow) and wants to actively collaborate with clinicians, data scientists, and multidisciplinary teams to drive impactful research outcomes.

Research Focus

• Stem Cell Biology and Hematopoiesis
• Megakaryocyte Differentiation and Platelet Biogenesis
• Ageing-related Disorders and Neurological Ailments
• Cell Signaling Pathways (Rap1 GTPase, Integrin Signaling)
• Stable Cell Line Development (Knockout & Overexpression Models)
• Flow Cytometry and Confocal Microscopy-based Functional Assays
• Transfection, Transduction, and Lentiviral Systems
• Cell-based Bioassays and Molecular Characterisation

Publications

1. Dhenge AC, Kale VP, Limaye LS. Enhancement of hematopoiesis and thrombopoiesis by pharmacological compounds valproic acid and all-trans retinoic acid. J Pharm Sci Tech Mgmt. 2015.
2. Dhenge AC, Limbkar K, Melinkeri S, Kale VP, Limaye L. Arachidonic acid and Docosahexaenoic acid enhance platelet formation from human apheresis-derived CD34(+) cells. Cell Cycle. 2017;16(10):979-990.
3. Limbkar K, Dhenge AC, Jadhav DD, Thulasiram HV, Kale V, Limaye L. Oral feeding with polyunsaturated fatty acids fosters hematopoiesis and thrombopoiesis in healthy and bone marrow-transplanted mice. J Nutr Biochem. 2017;47:94-105.
4. Dhenge A, Kuhikar R, Kale V, Limaye L. Regulation of differentiation of MEG01 to megakaryocytes and platelet-like particles by Valproic acid through Notch3-mediated actin polymerization. Platelets. 2019;30(6):780-795.
5. Ghalloussi D, Dhenge A, Bergmeier W. New insights into cytoskeletal remodeling during platelet production. J Thromb Haemost. 2019.
6. Lee RH, Piatt R, Dhenge A, et al. Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: mechanisms and implications. Science Translational Medicine. 2019.

Additional Information

Grants

Press Releases

Professional Profiles

Team Members

Collaborations

Biosketch

Dr. Somak Chowdhury is an interdisciplinary scientist working at the interface of genomics, microbiome science, computational biology, and translational medicine. With over 15 years of experience spanning microbial ecology, metagenomics, transcriptomics, precision medicine, and next-generation sequencing (NGS), his work focuses on transforming large- scale biological datasets into mechanistic insights that advance human health and biotechnology.

His research contributions have been published in internationally renowned journals, including Science, Nature Communications, Cell Press and Proceedings of the National Academy of Sciences. He is a recipient of the prestigious PNAS Cozzarelli Prize and Medac Research Award for his contributions to microbial ecology, microbial cooperation, and paleobiotechnology.

Throughout his career, Dr. Chowdhury has built expertise across diverse biological systems, ranging from soil and environmental microbiomes to ancient DNA and precision medicine applications. His interdisciplinary approach combines experimental biology, ecological theory, and advanced computational methods to address complex questions in host-associated microbial ecosystems.

Currently, Dr. Chowdhury serves as a Senior Scientist leading an interdisciplinary research group that investigates host–microbiome interactions through the lens of multi-omics technologies. His group integrates metagenomics, transcriptomics, metabolomics, and computational biology approaches to understand how microbial communities influence host physiology, metabolism, and disease processes. By developing reproducible analytical frameworks and leveraging large-scale biological datasets, his research aims to uncover mechanistic insights that can be translated into next-generation diagnostics, precision therapeutics, and preventive healthcare strategies.

Research Focus

Publications

1. Klapper, M., Hübner, A., Ibrahim, A., Wasmuth, I., Borry, M., Haensch, V. G., Zhang, S., Al-Jammal, W. K., Suma, H., Fellows Yates, J. A., et al. (2023). Natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic. Science, 380(6645), 619–624.
   Significance: Landmark study reconstructing ancient bacterial natural products from Neanderthal microbiomes and establishing a new paradigm in paleobiotechnology.
2. Zhang, S., Mukherji, R., Chowdhury, S., Reimer, L., & Stallforth, P. (2021). Lipopeptide mediated bacterial interaction enables cooperative predator defense. Proceedings of the National Academy of Sciences, 118(6), e2013759118.
   Significance: Recipient of the 2021 PNAS Cozzarelli Prize; revealed cooperative microbial defense mechanisms.
3. Zhang, S., Schlabach, K., Carrillo, V. H. P., Ibrahim, A., Nayem, S., Komor, A., Mukherji, R., Chowdhury, S., Reimer, L., Trottmann, F., et al. (2025). A chemical radar allows bacteria to detect and kill predators. Cell, 188(9), 2495–2504.
   Significance: Demonstrates sophisticated bacterial sensing mechanisms with implications for microbial ecology and biotechnology.
4. Malik, A. A., Puissant, J., Buckeridge, K. M., Goodall, T., Jehmlich, N., Chowdhury, S., Gweon, H. S., Peyton, J. M., Mason, K. E., van Agtmaal, M., et al. (2018). Land use driven change in soil pH affects microbial carbon cycling processes. Nature Communications, 9(1), 3591.
   Significance: High-impact work linking environmental change to microbial ecosystem functioning.
5. Chowdhury, S., Lange, M., Malik, A. A., Goodall, T., Huang, J., Griffiths, R. I., & Gleixner, G. (2022). Plants with arbuscular mycorrhizal fungi efficiently acquire nitrogen from substrate additions by shaping the decomposer community composition and their net plant carbon demand. Plant and Soil, 475(1), 473–490.
   Significance: First-author study elucidating nutrient acquisition mechanisms mediated by microbial communities.
6. Huang, J., Hammerbacher, A., Gershenzon, J., van Dam, N. M., Sala, A., McDowell, N. G., Chowdhury, S., Gleixner, G., Trumbore, S., & Hartmann, H. (2021). Storage of carbon reserves in spruce trees is prioritized over growth in the face of carbon limitation. Proceedings of the National Academy of Sciences, 118(33), e2023297118.
   Significance: Advances understanding of plant carbon allocation under environmental stress.
7. Baunach, M., Chowdhury, S., Stallforth, P., & Dittmann, E. (2021). The landscape of recombination events that create nonribosomal peptide diversity. Molecular Biology and Evolution, 38(5), 2116–2130.
   Significance: Provides evolutionary insights into natural product diversification.
8. Kumbhare, S. V., Kumar, H., Chowdhury, S., Dhotre, D. P., Endo, A., Mättö, J., Ouwehand, A. C., Rautava, S., Joshi, R., Patil, N. P., et al. (2017). A cross-sectional comparative study of gut bacterial communities of Indian and Finnish children. Scientific Reports, 7(1).
   Significance: One of the early international comparative human microbiome studies.
9. Ding, S., Lange, M., Lipp, J., Schwab, V. F., Chowdhury, S., Pollierer, M. M., Krause, K., Li, D., Kothe, E., Scheu, S., et al. (2020). Characteristics and origin of intact polar lipids in soil organic matter. Soil Biology and Biochemistry, 151, 108045.
   Significance: Integrates microbial ecology with biogeochemical cycling.
10. Malik, A. A., Chowdhury, S., Schlager, V., Oliver, A., Puissant, J., Vázquez, P. G. M., Jehmlich, N., von Bergen, M., Griffiths, R. I., & Gleixner, G. (2016). Soil fungal:bacterial ratios are linked to altered carbon cycling. Frontiers in Microbiology, 7, 1247.
    Significance: Foundational work connecting microbial community composition to ecosystem carbon dynamics.

Additional Information

Grants

🏆   PNAS Cozzarelli Prize (2021)

🏆   Medac Research Award (2023)

🎓   DAAD Long-Term Doctoral Fellowship

Press Releases

Professional Profiles

Team Members

Collaborations

Dr. Chowdhury has extensive experience leading interdisciplinary teams of laboratory scientists, computational biologists, and analysts. He is passionate about building reproducible scientific systems that enable rapid, high-quality research while fostering collaborative environments across academia, healthcare, and industry.

His approach combines scientific rigor, technological innovation, and effective communication to bridge the gap between complex biological data and meaningful real-world applications.

Biosketch

To understand fundamental mechanisms that safeguard proteome and translatome integrity in neurons and to translate these insights into strategies for early diagnostics in brain disorders like in autism spectrum disorder (ASD).

Research Focus

• Genetics of Autism Spectrum Disorder
• Decoding ribosome machinery
• Epitranscriptome-based Translation regulation

Publications

1. D’Souza MN, Gowda NKC et al. Altering rRNA 2’O-methylation pattern during neuronal differentiation is regulated by FMRP. RNA Biology (2025). Corresponding Author
2. Durbagula S et al.. Gowda NKC Genetic insights into male ASD in Indian families. General Psychiatry (2024). Corresponding Author
3. Gowda NKC et al. NMDARmediated dynamic changes in m⁶A inversely correlate with neuronal translation. Sci Reports (2022).
4. D’Souza MN, Gowda NKC et al. FMRP interacts with C/D box snoRNA and regulates rRNA methylation. iScience (2018).
5. Gowda NKC et al. Fes1/HspBP1 mimic substrate to release misfolded proteins from Hsp70. Nature Str Mol Bio (2018).
6. Gowda NKC et al. Cytosolic splice isoform of Fes1 required for degradation of misfolded proteins in yeast. Mol Biol Cell (2016).
7. Gowda NKC et al. Hsp70 nucleotide exchange factor Fes1 is essential for ubiquitindependent degradation of misfolded cytosolic proteins. PNAS (2013).

Additional Information

Invited Talk:

Invited talk on “Role of FMRP in translation regulation in human embryonic stem cells and its differentiation”, International Conference on Neurodegeneration: Biomarkers and Therapeutic targets, School of Life Science, JSS, Mysore, India. September 2023

Invited talk on “Exploration of 2’O methylation and FMRP pathways”, International Conference on OPEN Autism, St. John’s Research Institute, Bangalore, India. March 2023

Indian Academy of Neuroscience (IAN) – 4^th Satellite Symposium of Annual meeting, Theme: ‘Neuron – Glia Interaction: Recent concepts and Advances’. Dec 2021.

Conference Co-organized:

OPEN Autism – International Conference, CARE-ADD: St. John’s National Academy of Health Science, March 2023 Bangalore, India.

Virtual Guest lecturer on “Molecular Players in Autism and Neurodevelopmental disorder” – Nov 2022, St. John’s Research Institute, Bangalore, India.

Grants

• Principal Investigator – SERB Start-up Research Grant, 2024 – 2025.
• SERB International Travel Grant – 2023.
• Principal Investigator – Awarded SERB-NPDF, India, 2019-2021.
• Awarded fellowship from Federation of European Biochemical Societies (FEBS) / Young Scientists Forum (YSF), 2013-2014.

Press Releases

Professional Profiles

Team Members

• 👤 Shreya D
• 👤 Darshan

Collaborations

• St. John’s Research Institute
• CBR-IISc
• DBG-IISc
• MAHE

Biosketch

Poulomi completed doctoral degree at Manipal University, India (2012–2017). Poulomi’s PhD work focused on elucidating the molecular mechanisms underlying Epithelial-to-Mesenchymal Transition (EMT) during neural crest cell formation and cancer metastasis (Banerjee et al., Stem Cells, 2016; Banerjee et al., Journal of Molecular Medicine, 2017).

During her postdoctoral tenure at the UK Dementia Research Institute, University of Edinburgh (2017–2025) with Prof Siddharthan Chandran and Prof Josef Priller, Poulomi investigated the cellular and molecular basis of neuroinflammation, a hallmark of many neurological disorders. Her work in Amyotrophic Lateral Sclerosis (ALS) demonstrated cell-autonomous dysfunction of myeloid cells, including microglia and peripheral macrophages, contributing to a pro-inflammatory milieu and accelerated motor neuron degeneration (Banerjee et al., Stem Cell Research, 2021; Journal of Pathology, 2022; Science Advances, 2023). Additionally, Poulomi explored the effect of proteinopathies, particularly tau accumulation, on microglial inflammation and synaptic dysfunction in the context of Progressive Supranuclear Palsy (PSP), a pure form of tauopathy.

Beyond neurodegeneration, Poulomi studied neuron–microglia interactions in Fragile X Syndrome (commonest known genetic cause of Autism and intellectual disability) using patient-derived iPSC microglia, showing that microglial activation drives neuronal hyperexcitability (Banerjee et al., bioRxiv, 2024). Collectively, her research highlights neuroinflammation as a contributory mechanism across neurodegenerative and neurodevelopmental disorders.

Research Focus

The burden of non-communicable neurological disorders in India has nearly doubled over the past three decades, thereby highlighting a pressing need to identify novel disease-modifying strategies. Unravelling how the human brain functions and why it breaks down in disease remains one of the most dynamic areas of neuroscience research.

While neurodegenerative diseases like Alzheimer’s and Parkinson’s are known to affect neurons, recent research shows that the supporting cells in brain—called glial cells—also play a major role. When these cells don’t function properly, they can trigger inflammation, reduce support to neurons, and contribute to neuronal damage. To this end, neuroinflammation characterised by dysfunction of myeloid-lineage cells—such as CNS-resident microglia and circulating monocytes and macrophages, has become one of the key pathologies in neurological diseases. Importantly, the myeloid cell signature—particularly from blood—may serve as a biological indicator of disease stage, offering a path toward scalable, non-invasive diagnostic tests for detecting and characterizing neurological disorders. Separately, genetics plays an important factor in determining the vulnerability of an individual to neurological diseases —but most studies so far have focused on European populations, leaving a gap in understanding how they affect diverse population, including those in India.

Poulomi’s lab at SKAN RT is currently focusing on Parkinson’s disease (PD), a common neurodegenerative disorder that affects a significant number of individuals in India and currently lacks effective disease-modifying therapies. PD is characterized by α-synuclein accumulation and loss of dopaminergic neurons, leading to motor and non-motor symptoms, with growing evidence linking neuroinflammation to disease progression. While PD predominantly affects older adults, early-onset PD (EOPD), diagnosed before 40–50 years of age, accounts for 10–20% of cases and has a strong genetic basis. Notably, studies from India report a higher incidence of EOPD; however, the underlying genetic drivers and the role of neuroinflammation in Indian PD remain poorly understood.

Current Research Objectives

1. Map the molecular signatures of brain ageing in the Indian population using post-mortem brain tissue from individuals without neurological disease
2. Map genotype–phenotype relationships in early-onset Parkinson’s disease using genetics and blood-based markers
3. Identify molecular mechanisms in early neuron–microglia interactions in early-onset Parkinson’s disease using patient iPSC-derived brain cells.

Team Members

• Gargi Prasad Saradadevi (PhD)
• Moumita Paul (PhD)

Publications

1. Banerjee, P., Das Sharma, S., Burr, K., Morris, K., Ritakari, T., Baxter, P., Cooper, J., Cardinalli, A., Subash, S., Paza, E., Story, D., Chattarji, S., Kind, P. C., Carragher, N. O., Thangaraj Selvaraj, B., Priller, J., & Chandran, S. (2024). Human induced pluripotent stem cell-derived microglia contribute to the pathophysiology of Fragile X syndrome via increased RAC1 signaling. 10.1101 (Under review)
2. Banerjee, P., Mehta, A.R., Nirujogi, R.S., et al. 2022. Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration. Sci. Adv.9, eabq0651(2023). DOI: 10.1126
3. Kenkhuis, B., van Eekeren, M., Parfitt, D. A., Ariyurek, Y., Banerjee, P., Priller, J., van der Weerd, L., & van Roon-Mom, W. (2022). Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia. Stem cell reports, 17(6), 1351–1365.
4. Banerjee, P, Elliott, E, Rifai, O, O’shaughnessy, J, Mcdade, K, Abrahams, S, Chandran, S, Smith, C & Gregory, JM 2021, ‘NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis’, The Journal of Pathology 256(3), 262–268.
5. Perkins, E. M., Burr, K., Banerjee, P., Mehta, A. R., Dando, O., Selvaraj, B., Suminaite, D., Nanda, J., Henstridge, C. M., Gillingwater, T. H., Hardingham, G. E., Wyllie, D. J. A., Chandran, S., & Livesey, M. R. (2021). Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction. Molecular Neurodegeneration, 16(1),13.
6. Banerjee, P., Paza, E., Perkins, E. M., James, O. G., Kenkhuis, B., Lloyd, A. F., Burr, K., Story, D., Yusuf, D., He, X., Backofen, R., Dando, O., Chandran, S., & Priller, J. (2020). Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells. Stem Cell Research, 49, 102046.
7. Banerjee, P., Surendran, H., Bharti, K., Morishita, K., Varshney, A., & Pal, R. (2018). Long Noncoding RNA RP11-380D23.2 Drives Distal-Proximal Patterning of the Lung by Regulating PITX2 Expression. STEM CELLS, (Dayton, Ohio), 36(2), 218–229.
8. May-Simera, H. L., Wan, Q., Jha, B. S., Hartford, J., Khristov, V., Dejene, R., Chang, J., Patnaik, S., Lu, Q., Banerjee, P., Silver, J., Insinna-Kettenhofen, C., Patel, D., Lotfi, M., Malicdan, M., Hotaling, N., Maminishkis, A., Sridharan, R., Brooks, B., … Bharti, K. (2018). Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells. Cell Reports, 22(1), 189–205.
9. Shetty, R., Joshi, D., Jain, M., Vasudevan, M., Paul, J. C., Bhat, G., Banerjee, P., Abe, T., Kiyonari, H., Vijayraghavan, K., & Inamdar, M. S. (2018). Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. Scientific Reports, 8(1), 5632.
10. Banerjee, P., Dutta, S., & Pal, R. (2016). Dysregulation of Wnt-Signaling and a Candidate Set of miRNAs Underlie the Effect of Metformin on Neural Crest Cell Development. STEM CELLS, (Dayton, Ohio), 34(2), 334–345.
11. Banerjee, P., Surendran, H., Chowdhury, D. R., Prabhakar, K., & Pal, R. (2016). Metformin mediated reversal of epithelial to mesenchymal transition is triggered by epigenetic changes in E-cadherin promoter. Journal of Molecular Medicine. 94(12), 1397–1409.
12. Banerjee, P., Venkatachalam, S., Mamidi, M. K., Bhonde, R., Shankar, K., & Pal, R. (2015). Vitiligo patient-derived keratinocytes exhibit characteristics of normal wound healing via epithelial to mesenchymal transition. Experimental Dermatology, 24(5), 391–393
13. Banerjee, P., Bhonde, R. R., & Pal, R. (2013). Diverse roles of metformin during peri-implantation development: Revisiting novel molecular mechanisms underlying clinical implications. Stem Cells and Development. 22(22), 2927–2934.

Additional Information

Invited Talk:

• Invited Flash talk at Stem Cell Models of Neurodegeneration (SCMND), Edinburgh, 2025
• Invited speaker for Women in Autophagy (WIM) network; 2025
• Invited speaker for Gulmohar postdoc series (arranged by National Centre of Biological Sciences, India) 2025
• Invited speaker for ENCALS (European Network to Cure ALS) 2022: Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contribute to neurodegeneration.
• Flash talk in EMBO microglia workshop 2021 and UKDRI Connectome 2021: Disrupted autophagy leads to cell autonomous immune dysfunction in human iPSC-derived C9orf72-ALS microglia.

Grants

🏆  Rising Star Award from International Brain Research Organisation (IBRO), 2025

🏆  RS MacDonald Seed Corn Award, Edinburgh Neuroscience, 2021

Press Releases

• Boosting brain immune cell waste clearance could provide new drug target for MND, UK Dementia Research Institute (UKDRI), 21 April 2023 Link for details
• India’s 2025 IBRO Rising Stars: In conversation with Poulomi Banerjee and Proloy Das, Indian Bioscience, 15 September 2025 Link for details

Professional Profiles

Collaborations

• Dr Jyoti Nangalia, Group Leader, Wellcome Sanger Institute, United Kingdom
• Dr Vikram Holla, Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS)
• Dr. Pramod Kumar Pal, Senior Consultant-Parkinson’s Disease and Movement Disorders, Happiest Health Systems Pvt. Ltd. and SKAN-RT

Biosketch

Dr. Yogesh Shouche is currently working as Director at SKAN ResearchTrust Bengluru. He started his career as scientist National Centre for Cell Science (NCCS) in Pune, India. After working on different aspect of microbial, especially bacterial diversity of various ecological niches, his thrust area of research is now to understand succession of microbial communities in human gut during development and their role in health and diseases. He is working since 25 years in the field of microbial ecology, microbial molecular taxonomy and biodiversity; published more than 400 publications in journals of relevant area; reviewed publications in International journals like FEMS Ecology, International Journal of Systematic and Evolutionary Microbiology and Microbial Ecology. He is also on Editorial board of prestigious journals like Current Science, PlosOne etc. He is fellow of Maharashtra Academy of Sciences, Indian National Science Academy and National Academy of Sciences India.

During his tenure at NCCS he established Microbial Culture Collection (MCC), now known as National Center for Microbial Resource. It holds more than 150,000 bacteria and fungi in its collection recognized by WFCC (World Federation of Culture Collection). MCC is also recognized as International Depositary Authority (IDA) and is Designated Repository by Ministry of Environment, Forests & Climate Change, Government of India under the Biological Diversity Act 2002. In September 2018, Department of Biotechnology extended the mandate of this repository to include Anti Microbial Resistant microbes. He also initiated ambitious project on mapping of human microbiome of Indian population across diverse biogeographic regions.

After successful career at NCCS for 32 years, he joined Azim Premji University from 1^st March 2022 and from August 2023 he took over as Director of SKAN Research Trust. He was also on the member of the Executive Boards of International Society for Systematics of Prokaryotes till August 2023 and presently on Executive Board of World Federation of Culture Collections. As a recognition of his contributions, recently a genus has been named in his honor Shouchella. Interestingly, after recent re classification this genus now contains well known probiotic species. Bacillus clausii is now renamed as Shouchella clausii.

Research Focus

• Human gut microbiome diversity in Indian populations
  Dr Shouche’s research seeks to understand how India’s exceptional dietary, geographical, ethnic and socioeconomic diversity shapes the human gut microbiome. A major component of this work has been the development of India-specific microbiome reference data, including the initiation of a pan-India human microbiome mapping programme and studies of rural, urban and tribal communities that are underrepresented in international datasets.
• Microbiome contributions to health, disease and therapeutic response
  A central interest is the relationship between microbial community structure and human diseases, particularly diabetes, obesity, coeliac disease, non-coeliac gluten sensitivity, inflammatory bowel disease, kidney-stone disease, cardiovascular disorders and neurological conditions. This work combines clinical phenotyping with metagenomics, metabolomics, multi-omics and intervention studies to identify microbiome-associated mechanisms, biomarkers and potential therapeutic targets.
• Microbial cultivation, functional microbiology and microbiome-derived bioactives
  Dr Shouche’s programme extends beyond community profiling to the cultivation and functional characterisation of microorganisms. His interests include culturomics, anaerobic gut microorganisms, microbial metabolic functions, intermicrobial antagonism and the discovery of microbiome-derived compounds with anti-infective, anti-inflammatory, antidiabetic and other therapeutic properties. His leadership in establishing the National Centre for Microbial Resource provides an important infrastructure for this work.
• Microbial systematics, genomics and biological-resource development
  Dr Shouche has made foundational contributions to molecular microbial taxonomy in India. His work encompasses phylogenetics, whole-genome analysis, identification and description of novel microbial taxa, microbial preservation and the development of nationally important culture collections. He established a major microbial repository that became an International Depositary Authority under the Budapest Treaty and a national repository under India’s Biological Diversity Act.
• Environmental microbiomes, antimicrobial resistance and host–microbe interactions
  Another major interest is the movement of microorganisms and antimicrobial-resistance determinants across humans, animals and the environment. This includes studies of sewage, pharmaceutical-manufacturing wastewater, environmental resistomes and public-health surveillance, as well as pioneering investigations of mosquito-associated microorganisms and their influence on the transmission of dengue and Japanese encephalitis viruses.

Team Members

Publications

1. Foundational perspective on the Indian gut microbiome
   Shetty SA, Marathe NP, Shouche YS.
   “Opportunities and challenges for gut microbiome studies in the Indian population.”
   Microbiome. 2013;1:24.
   DOI: 10.1186/2049-2618-1-24.
2. Identification of distinctive features of the Indian gut microbiome
   Bhute S, Pande P, Shetty SA, et al.; Shouche YS.
   “Molecular Characterization and Meta-Analysis of Gut Microbial Communities Illustrate Enrichment of Prevotella and Megasphaera in Indian Subjects.”
   Frontiers in Microbiology. 2016;7:660.
   DOI: 10.3389/fmicb.2016.00660.
3. Diet-associated gut-microbiome variation in Indian tribal populations
   Ebel ER, Kulkarni AS, Mongad DS, et al.; Shouche YS, Sonnenburg JL, Dhotre DP.
   “Gut microbiomes of tribal communities in India vary with dairy and grain consumption.”
   Gut Microbes. 2026;18(1):2694242.
   DOI: 10.1080/19490976.2026.2694242.
4. Environmental reservoirs of multidrug resistance
   Marathe NP, Regina VR, Walujkar SA, Charan SS, Moore ER, Larsson DG, Shouche YS.
   “A treatment plant receiving waste water from multiple bulk drug manufacturers is a reservoir for highly multidrug-resistant integron-bearing bacteria.”
   PLOS ONE. 2013;8(10):e77310.
   DOI: 10.1371/journal.pone.0077310.
5. Genomics of an important malaria vector
   Jiang X, Peery A, Hall AB, et al.; Shouche Y, Tu Z.
   “Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi.”
   Genome Biology. 2014;15:459.

Additional Information

He has secured grants worth over 200 Cr in his tenure at NCCS and given several talks across India and written popular science articles in English and Marathi. He enjoys interacting with students and motivating them.

Grants

Press Releases

Professional Profiles

Collaborations

As a Director of SKAN, he is instrumental in fostering several national and international collaborations including those with NIMHANS, St John Hospital, Quadram Institute Bioscience and Cambridge University.